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dc.creatorSuwalsky Weinsymer, Mario
dc.creatorZatta, Paolo
dc.date.accessioned2016-12-27T21:48:48Z
dc.date.available2016-12-27T21:48:48Z
dc.date.issued2001
dc.identifier.isbn978-0-444-50811-9
dc.identifier.urihttp://hdl.handle.net/10533/165041
dc.description.abstractAluminum is able to deeply modify the physico-chemical properties of natural as well as artificial biomembranes. Such modifications,which are strongly correlated to the metal speciation chemical characteristics, can alter relevant cellular, biochemical and physiological parameters (e.g., fluidity, rigidity, transduction of signals, channel permeability and protein activity). In Alzheimer's disease a profound alteration of the cell membrane both in neuronal as well as in non-neuronal cells has been reported. Herein, the most relevant data regarding the interaction between aluminum and cell membranes has been summarized. How the metal ion could eventually have an important role as an aggravating factor in Alzheimer's disease, as well as in other neurodegenerative diseases where the metal ion has been reported to be abnormally accumulated, is also discussed.
dc.language.isoeng
dc.relationinstname: Conicyt
dc.relationreponame: Repositorio Digital RI2.0
dc.relationinstname: Conicyt
dc.relationreponame: Repositorio Digital RI 2.0
dc.titleALUMINUM, MEMBRANES AND ALZHEIMERS DISEASE
dc.typeCapitulo de libro
dc.bibliographicCitation.stpage279
dc.bibliographicCitation.endpage291
dc.identifier.folio1990289
dc.description.conicytprogramFONDECYT
dc.relation.projectidinfo:eu-repo/grantAgreement/Fondecyt/1990289
dc.relation.setinfo:eu-repo/semantics/dataset/hdl.handle.net/10533/93479
dc.rights.driverinfo:eu-repo/semantics/openAccess
dc.type.driverinfo:eu-repo/semantics/bookPart
dc.description.shortconicytprogramFONDECYT
dc.title.libroALUMINIUM AND ALZHEIMERS DISEASE
dc.creator.libroChristopher, Exley
dc.description.libropages452
dc.publisher.editorialELSEVIER


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