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dc.creatorJara, Evelyn L
dc.creatorMuñoz-Durango, Natalia
dc.creatorLlanos, Carolina
dc.creatorFardella, Carlos
dc.creatorGonzález-Muñoz, Pablo Alberto
dc.creatorBueno, Susan M
dc.creatorKalergis, Alexis M
dc.creatorRiedel, Claudia A
dc.date.accessioned2018-10-01T19:27:41Z
dc.date.available2018-10-01T19:27:41Z
dc.date.issued2017es_CL
dc.identifier.urihttp://hdl.handle.net/10533/220728
dc.description.abstractAccumulating evidence suggests a close bidirectional communication and regulation between the neuroendocrine and immune systems. Thyroid hormones (THs) can exert responses in various immune cells, e.g., monocytes, macrophages, natural killer cells, and lymphocytes, affecting several inflammation related processes (such as, chemotaxis, phagocytosis, reactive oxygen species generation, and cytokines production). The interactions between the endocrine and immune systems have been shown to contribute to pathophysiological conditions, including sepsis, inflammation, autoimmune diseases and viral infections. Under these conditions, TH therapy could contribute to restoring normal physiological functions. Here we discuss the effects of THs and thyroid stimulating hormone (TSH) on the immune system and the contribution to inflammation and pathogen clearance, as well as the consequences of thyroid pathologies over the function of the immune system. (C) 2017 European Federation of Immunological Societies. Published by Elsevier B.V. All rights reserved. Keywords Author Keywords:Thyroid hormones; Inflammation; Immunity; TSHes_CL
dc.language.isoeng
dc.relationinstname: Conicyt
dc.relationreponame: Repositorio Digital RI2.0
dc.relation.urihttps://www.ncbi.nlm.nih.gov/pubmed/28216261es_CL
dc.rightsinfo:eu-repo/semantics/openAccesses_CL
dc.rightsAttribution-NonCommercial-NoDerivs 3.0 Chile*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/cl/*
dc.titleModulating the function of the immune system by thyroid hormones and thyrotropines_CL
dc.typeArticulo
dc.identifier.folio1140011es_CL
dc.relation.projectidinfo:eu-repo/grantAgreement//1140011es_CL
dc.relation.setinfo:eu-repo/semantics/dataset/hdl.handle.net/10533/93477
dc.rights.driverinfo:eu-repo/semantics/openAccess
dc.title.journalImmunology Letterses_CL
dc.type.driverinfo:eu-repo/semantics/article
dc.type.openaireinfo:eu-repo/semantics/publishedVersion


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