Dehydroascorbic acid promotes cell death in neurons under oxidative stress: a protective role for astrocytes
Author
Garcia-Krauss, AndréaFerrada, Luciano
Astuya, Allisson
Salazar, Katterine
Cisternas, Pedro
Martínez, Fernando
Ramírez, Eder
Nualart-Santander, Francisco Javier
Abstract
Ascorbic acid (AA), the reduced form of vitamin C, is incorporated into neurons via the sodium ascorbate co-transporter SVCT2. However, this transporter is not expressed in astrocytes, which take up the oxidized form of vitamin C, dehydroascorbic acid (D
Contest
Concurso Nacional Regular 2014Date de publicación
2016Journal title
Molecular Neurobiology