A conserved homodimeric interface of the Hanta virus Gc glycoprotein directs viral particle assembly, acid-induced spike dissociation and membrane fusion
Author
Bignon, Eduardo AGuardado-Calvo, P
Rey, F A
Tischler-Dworschak, Nicole
Abstract
Rodent-transmitted hantaviruses (Bunyaviriales order) are human pathogens that can reach fatality rates up to 50%. Their
envelope glycoproteins, Gn and Gc, are derived from a precursor polyprotein and upon assembly onto viral particles they
form (Gn/Gc)4
Date de publicación
2018Associated congress
28°