Repositorio CONICYT Producción científica asociada a proyectos y becas financiadas por CONICYT

  • Login
Más tipos
  • Programa
  • Institución
  • Año de concurso
  • Disciplinas
    • Disciplinas Fondecyt
    • Áreas Fondef
    • Sector de aplicación
    • Clasificaciones OECD
  • Regiones de Chile
  • Menu
    • Programa
    • Institución
    • Año de concurso
    • Disciplinas Fondecyt
    • Áreas Fondef
    • Sector de aplicación
    • Clasificaciones OECD
    • Regiones de Chile
View Item 
  •   DSpace Home
  • Resultados de Proyectos
  • Productividad
  • Capítulos de Libros
  • View Item
  •   DSpace Home
  • Resultados de Proyectos
  • Productividad
  • Capítulos de Libros
  • View Item
JavaScript is disabled for your browser. Some features of this site may not work without it.

Immune Evasion by Herpes Simplex Viruses

Type
Capitulo de libro
Program
Programa FONDECYT
Conicyt Instrument
Proyectos Regulares
Author
Retamal-Díaz, Angello Ricardo
Tognarelli-Torres, Eduardo Ignacio
Kalergis, Alexis M
Bueno, Susan M
González-Muñoz, Pablo Alberto
Abstract
Infection with herpes simplex viruses type 1 (HSV-1) and type 2 (HSV-2) is extremely frequent in the human population, as well as recurrent reactivations due to lifelong infection. Infection and persistence of HSVs within healthy individuals likely results as a consequence of numerous molecular determinants evolved by these pathogens to escape both immediate and long-term host antiviral mechanisms. Indeed, HSVs harbor an arsenal of proteins ...   Ver más
Infection with herpes simplex viruses type 1 (HSV-1) and type 2 (HSV-2) is extremely frequent in the human population, as well as recurrent reactivations due to lifelong infection. Infection and persistence of HSVs within healthy individuals likely results as a consequence of numerous molecular determinants evolved by these pathogens to escape both immediate and long-term host antiviral mechanisms. Indeed, HSVs harbor an arsenal of proteins that confer them stealth by negatively modulating immune function. Consequently, these viruses perpetuate within the host, altogether silently shedding onto other individuals. In this chapter, we discuss HSV determinants that interfere with cellular antiviral factors, as well as viral determinants that hamper innate and adaptive immune components intended to control such microbes. The identification of HSV evasion molecules that modulate the immune system, as well as the understanding of their mechanisms of action, should facilitate the design of novel prophylactic and therapeutic strategies to overcome infection and disease elicited by these viruses. This chapter is intended to provide an overview of the evasion mechanisms evolved by herpes simplex viruses to escape numerous host antiviral mediators. Keywords: immune evasion, innate immunity, adaptive immunity, antiviral response   Ver menos
Project Id
1140011
Contest
Concurso Nacional Regular 2014
Book's title
Herpesviruses
Publication date of the book
2016
URI
https://www.intechopen.com/books/herpesviridae/immune-evasion-by-herpes-simplex-viruses
https://books.google.cl/books?id=pnqQDwAAQBAJ&pg=PR2&lpg=PR2&dq=Jozsef+Ongradi++isbn&source=bl&ots=re1yZHfaII&sig=ACfU3U3QPLd1N5S7uecwc3q7DfrNWfwg0Q&hl=es&sa=X&ved=2ahUKEwjN9ZTUoIfiAhXHE7kGHc_8CcsQ6AEwCXoECAgQAQ#v=onepage&q=Jozsef%20Ongradi%20%20isbn&f=false
Start page
104
End page
146
Metadata
Show full item record

CONICYT Comisión Nacional de Investigación Científica y Tecnológica

Moneda 1375, Santiago de Chile. Teléfono (56 2) 365 44 00

¿NECESITAS AYUDA?

Centro de ayuda OIRS

o llámanos directamente al

(02) 365 44 00

  • Políticas de Privacidad
  • Gobierno Transparente
  • Trabaja con Nosotros
  • Donación de Bienes
  • Webmail
  • Contacto
  • Acerca de RI 2.0
  • Otros repositorios
  • Políticas
  • Recursos de Información Conicyt
  • Ayuda
  • FAQs
Material de Donación
Contacto:

Moneda 1375, piso 13, Santiago.
Teléfono: (+562) 36 54 462.
Horario: L-J: 09:00 a 17:00 hrs.                   Vi: 09:00 a 14:00 hrs.

biblioteca@conicyt.cl

Nuevo Depósito
Política de Depósito

Browse

All of DSpaceCommunities & CollectionsThis CollectionAuthorsTitlesProject IdDocument TypeSubject

CONICYT Comisión Nacional de Investigación Científica y Tecnológica

Moneda 1375, Santiago de Chile. Teléfono (56 2) 365 44 00

¿NECESITAS AYUDA?

Centro de ayuda OIRS

o llámanos directamente al

(02) 365 44 00

  • Políticas de Privacidad
  • Gobierno Transparente
  • Trabaja con Nosotros
  • Donación de Bienes
  • Webmail
  • Contacto
  • Acerca de RI 2.0
  • Otros repositorios
  • Políticas
  • Recursos de Información Conicyt
  • Ayuda
  • FAQs