p120-catenin is necessary for neuroprotection induced by CDK5 silencing in models of Alzheimer's disease

Type
Articulo
Program
There is not a program associated
Conicyt Instrument
There is not a Conicyt instrument associated
Author
Uribe-Arias, A.
Posada-Duque, R. A.
González-Billault, C.
Villegas, A.
Lopera, F.
Cardona-Gómez, G. P.
Abstract
Cyclin-dependent kinase 5 (CDK5) plays important roles in synaptic function. Its unregulated over-activation has been, however, associated with neurodegeneration in Alzheimer's disease. Our previous studies revealed that CDK5 silencing ameliorates tauopat
Project Id
15150012
Contest
There is not a contest associated
Date de publicación
2016
Journal title
Journal of Neurochemistry
URI
https://doi.org/10.1111/jnc.13697
Metadata
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