p120-catenin is necessary for neuroprotection induced by CDK5 silencing in models of Alzheimer's disease

Type
ArticuloProgram
There is not a program associatedConicyt Instrument
There is not a Conicyt instrument associatedAuthor
Uribe-Arias, A.Posada-Duque, R. A.
González-Billault, C.
Villegas, A.
Lopera, F.
Cardona-Gómez, G. P.
Abstract
Cyclin-dependent kinase 5 (CDK5) plays important roles in synaptic function. Its unregulated over-activation has been, however, associated with neurodegeneration in Alzheimer's disease. Our previous studies revealed that CDK5 silencing ameliorates tauopat
Project Id
15150012Contest
There is not a contest associatedDate de publicación
2016Journal title
Journal of Neurochemistry